Research Findings
Lutein and AMD
1. Landrum JT and Bone RA. Lutein, zeaxanthin, and the macular pigment. Arch Biochem Biophys 385: 28-40., 2001.
2. Beatty S, Boulton M, Henson D, Koh HH, and Murray IJ. Macular pigmentand age related macular degeneration. Br J Ophthalmol 83: 867-877., 1999.
3. Aleman TS, Duncan JL, Bieber ML, de Castro E, Marks DA, Gardner LM, Steinberg JD, Cideciyan AV, Maguire MG, and Jacobson SG. Macular pigment and lutein supplementation in retinitis pigmentosa and usher syndrome. Invest Ophthalmol Vis Sci 42: 1873-1881., 2001.
4. Berendschot TT, Goldbohm RA, Klopping WA, van de Kraats J, van Norel J, and van Norren D. Influence of lutein supplementation on macular pigment, assessed with two objective techniques. Invest Ophthalmol Vis Sci 41:3322-3326., 2000.
5. Duncan JL, Aleman TS, Gardner LM, De Castro E, Marks DA, Emmons JM, Bieber ML, Steinberg JD, Bennett J, Stone EM, MacDonald IM, Cideciyan AV, Maguire MG, and Jacobson SG. Macular pigment and lutein supplementation in choroideremia. Exp Eye Res 74: 371-381., 2002.
6. Hammond BR, Johnson EJ, Russell RM, Krinsky NI, Yeum KJ, Edwards RB, and Snodderly DM. Dietary modification of human macular pigment density. Invest Ophthalmol Vis Sci 38: 1795-1801., 1997.
7. Johnson EJ, Hammond BR, Yeum KJ, Qin J, Wang XD, Castaneda C, Snodderly DM, and Russell RM. Relation among serum and tissue concentrations of lutein and zeaxanthin and macular pigment density. Am J Clin Nutr 71: 1555-1562., 2000.
8. Landrum JT, Bone RA, Joa H, Kilburn MD, Moore LL, and Sprague KE. A one year study of the macular pigment: the effect of 140 days of a lutein supplement. Exp Eye Res 65: 57-62., 1997.
9. Antioxidant status and neovascular age-related macular degeneration. Eye Disease Case-Control Study Group. Arch Ophthalmol 111: 104-109., 1993.
10. Seddon JM, Ajani UA, Sperduto RD, Hiller R, Blair N, Burton TC, Farber MD, Gragoudas ES, Haller J, Miller DT, and et al. Dietary carotenoids, vitamins A, C, and E, and advanced age-related macular degeneration. Eye Disease Case-Control Study Group. Jama 272: 1413-1420, 1994.
11. Curran-Celentano J, Hammond BR, Jr., Ciulla TA, Cooper DA, Pratt LM, and Danis RB. Relation between dietary intake, serum concentrations, and retinal concentrations of lutein and zeaxanthin in adults in a Midwest population. Am J Clin Nutr 74: 796-802., 2001
12. Bone RA, Landrum JT, Mayne ST, Gomez CM, Tibor SE, and Twaroska EE. Macular pigment in donor eyes with and without AMD: a case-control study. Invest Ophthalmol Vis Sci 42: 235-240, 2001.
13. Broekmans WM, Berendschot TT, Klopping-Ketelaars IA, de Vries AJ, Goldbohm RA, Tijburg LB, Kardinaal AF, and van Poppel G. Macular pigment density in relation to serum and adipose tissue concentrations of lutein and serum concentrations of zeaxanthin. Am J Clin Nutr 76: 595-603., 2002.
14. Bernstein PS, Zhao DY, Wintch SW, Ermakov IV, McClane RW, and Gellermann W. Resonance Raman measurement of macular carotenoids in normal subjects and in age-related macular degeneration patients. Ophthalmology 109: 1780-1787., 2002.
15. Snellen EL, Verbeek AL, Van Den Hoogen GW, Cruysberg JR, and Hoyng CB. Neovascular age-related macular degeneration and its relationship to antioxidant intake. Acta Ophthalmol Scand 80: 368-371., 2002.
Lutein and Cataracts
1. Lyle, B. J., J. A. Mares-Perlman, et al. (1999). "Antioxidant intake and risk of incident age-related nuclear cataracts in the Beaver Dam Eye Study." Am J Epidemiol 149(9): 801-9.
2. Yeum, K. J., A. Taylor, et al. (1995). "Measurement of carotenoids, retinoids, and tocopherols in human lenses." Invest Ophthalmol Vis Sci 36(13): 2756-61.
3. Chasan-Taber, L., W. C. Willett, et al. (1999). "A prospective study of carotenoid and vitamin A intakes and risk of cataract extraction in US women." Am J Clin Nutr 70(4): 509-16.
4. Brown, L., E. B. Rimm, et al. (1999). "A prospective study of carotenoid intake and risk of cataract extraction in US men." Am J Clin Nutr 70(4): 517-24.

